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4-hydroxyphenylacetic acid
CAS No. 156-38-7
4-hydroxyphenylacetic acid( —— )
Catalog No. M18084 CAS No. 156-38-7
4-Hydroxybenzeneacetate acid is considered to be slightly soluble (in water) and acidic. 4-Hydroxybenzeneacetate acid can be synthesized from acetic acid.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product Name4-hydroxyphenylacetic acid
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NoteResearch use only, not for human use.
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Brief Description4-Hydroxybenzeneacetate acid is considered to be slightly soluble (in water) and acidic. 4-Hydroxybenzeneacetate acid can be synthesized from acetic acid.
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Description4-Hydroxybenzeneacetate acid is considered to be slightly soluble (in water) and acidic. 4-Hydroxybenzeneacetate acid can be synthesized from acetic acid. It can be found throughout numerous foods such as Olives, Cocoa beans, Oats, and Mushrooms. 4-Hydroxybenzeneacetate acid can be found throughout all human tissues and in all biofluids. Within a cell, 4-Hydroxybenzeneacetate acid is primarily located in the cytoplasm and in the extracellular space.(In Vivo):4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1.
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In Vitro——
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In Vivo4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number156-38-7
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Formula Weight152.15
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Molecular FormulaC8H8O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL; 657.25 mM
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SMILESOC(=O)Cc1ccc(cc1)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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