Cart
sales@molnova.com
Naratriptan hydrochloride
CAS No. 143388-64-1
Naratriptan hydrochloride( Naratriptan HCl | Amerge | Naramig | GR-85548A )
Catalog No. M18015 CAS No. 143388-64-1
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 39 | In Stock |
|
| 25MG | 73 | In Stock |
|
| 50MG | 122 | In Stock |
|
| 100MG | 215 | In Stock |
|
| 200MG | 268 | In Stock |
|
| 500MG | 442 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNaratriptan hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionNaratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
-
DescriptionNaratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
-
In Vitro——
-
In Vivo——
-
SynonymsNaratriptan HCl | Amerge | Naramig | GR-85548A
-
PathwayOthers
-
TargetOther Targets
-
Recptor5-HT1
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number143388-64-1
-
Formula Weight371.93
-
Molecular FormulaC17H25N3O2S·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 35 mg/mL; 94.10 mM
-
SMILESCNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl
-
Chemical NameN-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
DUPA
DUPA is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.
-
Src Inhibitor 3
Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50 <3 nM in CSK HTRF, <4 nM in Caliper assay). Src Inhibitor 3 increases T cell proliferation induced by T cell receptor signaling.
-
α-CGRP (mouse, rat)
α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies.
