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L-Glutamic acid monosodium salt
CAS No. 142-47-2
L-Glutamic acid monosodium salt( Monosodium glutamate | Sodium glutamate | MSG )
Catalog No. M18010 CAS No. 142-47-2
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 31 | In Stock |
|
| 100MG | 43 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 57 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameL-Glutamic acid monosodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionL-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
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DescriptionMonosodium glutamate is one of the FLAVORING AGENTS used to impart a meat-like flavor. Medically it has been used to reduce blood ammonia levels in ammoniacal azotemia, therapy of hepatic coma, in psychosis, and INTELLECTUAL DISABILITY.
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In VitroCell Viability Assay Cell Line: SH-SY5Y, IMR-32, SK-N-BE(2)Concentration:2, 5, 10, 20 mM Incubation Time: 24 and 48 h Result:Reduced cell viability in a dose-dependent manner.
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In VivoAnimal Model:Crv4 mice model Dosage:3g/kg Administration:s.c., single dose Result:Reduced the number of Brn-3a+ RGCs by >70%.In the absence of mGlu1 receptor, MSG-induced retinal damage is diminished.Animal Model:CPF-induced rat model Dosage:750 mg/kg Administration:i.p.Result:Reduced CPF-induced oxidative stress by increasing the level of GSH and activity of GSH-related enzymes.
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SynonymsMonosodium glutamate | Sodium glutamate | MSG
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PathwayOthers
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TargetOther Targets
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RecptormGluR1
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number142-47-2
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Formula Weight169.11
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Molecular FormulaC5H8NO4·Na
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 100 mg/mL; 591.33 mM
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SMILESC(CC(=O)O)[C@@H](C(=O)[O-])N.[Na+]
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Chemical Namesodium (S)-2-amino-4-carboxybutanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liberatore F, et al. Permissive role for mglu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Sep 14. pii: S0306-4522(17)30640-1.
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