Anemoside B4
CAS No. 129741-57-7
Anemoside B4( Anemoside B4 )
Catalog No. M17928 CAS No. 129741-57-7
Anemoside B4 inhibits the secretion of IL-10.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 63 | In Stock |
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| 5MG | 28 | In Stock |
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| 10MG | 40 | In Stock |
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| 25MG | 65 | In Stock |
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| 50MG | 91 | In Stock |
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| 100MG | 135 | In Stock |
|
| 200MG | 198 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAnemoside B4
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NoteResearch use only, not for human use.
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Brief DescriptionAnemoside B4 inhibits the secretion of IL-10.
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DescriptionAnemoside B4 inhibits the secretion of IL-10.
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In VitroPulchinenoside C (Anemoside B4) can inhibit the secretion of IL-10; SSA, SSD and PNS up-regulated IL-2 expression. Pulchinenoside C (Anemoside B4), with IC50 value more than 390 ug/mL. Anemoside B4 inhibits cell proliferation. Pulchinenoside C (Anemoside B4) can significantly suppress the secretion of the inflammatory factor E-selectin by endothelial cells.
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In Vivo——
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SynonymsAnemoside B4
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorIL-10
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number129741-57-7
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Formula Weight1221.38
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Molecular FormulaC59H96O26
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL 102.34 mM;
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SMILESC[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@]45CC[C@H]([C@@H]4[C@H]4CC[C@@H]6[C@@]7(C)CC[C@H](O[C@@H]8OC[C@H](O)[C@H](O)[C@H]8O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@@](C)(CO)[C@@H]7CC[C@@]6(C)[C@]4(C)CC5)C(C)=C)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Huwentoxin IV
Selective NaV1.7 channel blocker. Preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). Inhibits the channel by binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration.
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R 56865
R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.
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Aneratrigine hydroch...
Aneratrigine hydrochloride is a sodium channel protein type 9 subunit blocker that may be used for the prevention or treatment of sodium channel blocker-related diseases.
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