ML133 HCl
CAS No. 1222781-70-5
ML133 HCl( —— )
Catalog No. M17888 CAS No. 1222781-70-5
ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 41 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 103 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | 268 | In Stock |
|
| 200MG | 347 | In Stock |
|
| 500MG | 585 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML133 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorKir2.1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1222781-70-5
-
Formula Weight313.82
-
Molecular FormulaC19H19NO·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 125 mg/mL; 398.32 mM
-
SMILESCl.COC1=CC=C(CNCC2=CC=CC3=C2C=CC=C3)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang HR, et al. ACS Chem Biol, 2011, 6(8), 845-856.
molnova catalog
related products
-
CDK5 inhibitor 20-22...
CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9.
-
VMY-1-103
A novel dansylated analog of purvalanol B, and a CDK inhibitor that inhibits cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B.
-
ON-013100
ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.
Cart
sales@molnova.com