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Polaprezinc
CAS No. 107667-60-7
Polaprezinc( Polaprezinc | Z 103 )
Catalog No. M17799 CAS No. 107667-60-7
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 33 | In Stock |
|
| 100MG | 49 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 122 | In Stock |
|
| 1G | 179 | In Stock |
|
Biological Information
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Product NamePolaprezinc
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NoteResearch use only, not for human use.
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Brief DescriptionPolaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
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DescriptionPolaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
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In Vitro——
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In VivoPolaprezinc (PZ) is an antiulcer drug and a chelating compound consisting of a zinc ion, L-carnosine, a β-alanine dipeptide and L-histidine. Polaprezinc exerts antioxidant effects and scavenges free radicals. The efficacy of Polaprezinc is reported for acute radiation proctitis in an animal model and demonstrates that Polaprezinc has an anti-inflammatory effect following exposure to radiation.
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SynonymsPolaprezinc | Z 103
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number107667-60-7
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Formula Weight289.63
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Molecular FormulaC9H12N4O3Zn
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Purity>98% (HPLC)
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SolubilityH2O : 3.37 mg/mL 11.68 mM; DMSO : < 1 mg/mL
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SMILESNCCC(=O)N1[Zn]OC(=O)[C@@H]1Cc1cnc[nH]1
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Chemical Namecatena-Poly(zinc-mu-(beta-alanyl-L-histidinato(2(-))-N,N(sup N),O:N(sup tau)))
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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t-OMe-Byakangelicin
(R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis.
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Sanggenol O
Sanggenol O? is an active product that can be extracted from Morus alba. Sanggenol O has hepatoprotective and neuroprotective activities with EC50s more than 80 μM in HepG2 and HT22 cells.
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7-hydroxycoumarinyl-...
7-hydroxycoumarinyl-γ-Linolenate is a γ-linolenic acid ester of 7-hydroxycoumarin (umbelliferone) that behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl-γ-linolenate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).
