Tetrahydrocoptisine

Research use only, not for human use.

Tetrahydrocoptisine has effective effects in suppressing inflammation. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process.

Tetrahydrocoptisine has effective effects in suppressing inflammation. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.

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Tyrosine Kinase

FLT3

NF-κB|ERK|p38 MAPK

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7461-02-1

323.34

C19H17NO4

>98% (HPLC)

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C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6

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(-20℃)

With Ice Pack

≥ 2 years