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SCH900776 S-isomer
CAS No. 891494-64-7
SCH900776 S-isomer( MK-8776 S-isomer )
Catalog No. M17644 CAS No. 891494-64-7
SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 110 | In Stock |
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| 2MG | 61 | In Stock |
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| 5MG | 92 | In Stock |
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| 10MG | 149 | In Stock |
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| 25MG | 264 | In Stock |
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| 50MG | 416 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSCH900776 S-isomer
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NoteResearch use only, not for human use.
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Brief DescriptionSCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
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DescriptionSCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
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In Vitro——
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In Vivo——
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SynonymsMK-8776 S-isomer
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PathwayOthers
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TargetOther Targets
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RecptorCDK2| Chk1| Chk2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number891494-64-7
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Formula Weight376.25
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Molecular FormulaC15H18BrN7
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL; 265.78 mM
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SMILESCn1cc(cn1)c1c2nc(c(c(n2nc1)N)Br)[C@H]1CCCNC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Guzi TJ, et al. Mol Y Ther, 2011, 10(4), 591-602.
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