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SCH900776 S-isomer

CAS No. 891494-64-7

SCH900776 S-isomer( MK-8776 S-isomer )

Catalog No. M17644 CAS No. 891494-64-7

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	110	In Stock
2MG	61	In Stock
5MG	92	In Stock
10MG	149	In Stock
25MG	264	In Stock
50MG	416	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SCH900776 S-isomer
Note

Research use only, not for human use.
Brief Description

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
Description

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
In Vitro

——
In Vivo

——
Synonyms

MK-8776 S-isomer
Pathway

Others
Target

Other Targets
Recptor

CDK2| Chk1| Chk2
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

891494-64-7
Formula Weight

376.25
Molecular Formula

C15H18BrN7
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 100 mg/mL; 265.78 mM
SMILES

Cn1cc(cn1)c1c2nc(c(c(n2nc1)N)Br)[C@H]1CCCNC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Guzi TJ, et al. Mol Y Ther, 2011, 10(4), 591-602.

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