Syk Inhibitor II( —— )

Catalog No. M17582 CAS No. 726695-51-8

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Syk Inhibitor II
Note

Research use only, not for human use.
Brief Description

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
Description

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

Syk
Research Area

——
Indication

——

Chemical Information

CAS Number

726695-51-8
Formula Weight

340.3
Molecular Formula

C14H15F3N6O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (14.69 mM)
SMILES

NCCNC1=NC(NC2=CC(C(F)(F)F)=CC=C2)=C(C(N)=O)C=N1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.Bioorg Med Chem. 2005 Aug 15;13(16):4936-51.

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