Glabridin( Glabridin | Q-100692 | KB289522 | S-176045 )

Catalog No. M17552 CAS No. 59870-68-7

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HNMR

HPLC

MSDS

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Product Name

Glabridin
Note

Research use only, not for human use.
Brief Description

Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels.
Description

Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.
In Vitro

——
In Vivo

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Synonyms

Glabridin | Q-100692 | KB289522 | S-176045
Pathway

Membrane Transporter/Ion Channel
Target

NMDAR
Recptor

T1 tyrosinase| T3 tyrosinase
Research Area

Others-Field
Indication

——

CAS Number

59870-68-7
Formula Weight

324.37
Molecular Formula

C20H20O4
Purity

>98% (HPLC)
Solubility

DMSO : 150 mg/mL. 462.43 mM;
SMILES

CC1(C=Cc2c(O1)ccc1c2OC[C@H](C1)c1c(cc(cc1)O)O)C
Chemical Name

(R)-4-(8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

1. Yokota Tm , et al. Pigment Cell Res. 1998 Dec;11(6):355-61.

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