Cart
sales@molnova.com
3-MATIDA
CAS No. 518357-51-2
3-MATIDA( 3-MATIDA )
Catalog No. M17529 CAS No. 518357-51-2
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
|
| 5MG | 70 | In Stock |
|
| 10MG | 114 | In Stock |
|
| 25MG | 234 | In Stock |
|
| 50MG | 381 | In Stock |
|
| 100MG | 565 | In Stock |
|
| 500MG | 1215 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name3-MATIDA
-
NoteResearch use only, not for human use.
-
Brief Description3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).
-
Description3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
-
In Vitro——
-
In Vivo——
-
Synonyms3-MATIDA
-
PathwayTyrosine Kinase
-
TargetTrk Receptor
-
RecptormGluR1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number518357-51-2
-
Formula Weight215.22
-
Molecular FormulaC8H9NO4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCc1c(sc(c1)C(=O)O)C(C(=O)O)N
-
Chemical Name3-Methyl-aminothiophene dicarboxylic acid; 5-(Amino(carboxy)methyl)-4-methylthiophene-2-carboxylic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Moroni, F., et al. 2002. Neuropharmacology. 42: 741-751.
molnova catalog
related products
-
CG 428
CG 428 is a potent tropomyosin receptor Kinase (TRK) Degrader (uSMITETM) with a DC50 of 0.36 nM. CG 428 comprises an analog of the pan-TRK inhibitor GNF-8625 joined by a linker to the cereblon E3 ligase ligand pomalidomide.
-
(3aR)-Selitrectinib
(6RS)-LOXO-195 is a potent and selective Trk tyrosine kinase inhibitor.
-
Cyclotraxin B
Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
