SU5402( SU5402 | SU-5402 | SU 5402 )

Catalog No. M17435 CAS No. 215543-92-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

SU5402
Note

Research use only, not for human use.
Brief Description

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
Description

SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μ M at VEGFR2, FGFR1, PDGFR β and EGFR respectively).
In Vitro

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In Vivo

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Synonyms

SU5402 | SU-5402 | SU 5402
Pathway

Angiogenesis
Target

EGFR
Recptor

FGFR1| PDGFRβ| VEGFR2
Research Area

Cancer
Indication

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CAS Number

215543-92-3
Formula Weight

296.32
Molecular Formula

C17H16N2O3
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 30 mg/mL; 101.24 mM
SMILES

CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O
Chemical Name

(Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid.