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SU5402

CAS No. 215543-92-3

SU5402( SU5402 | SU-5402 | SU 5402 )

Catalog No. M17435 CAS No. 215543-92-3

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SU5402
  • Note
    Research use only, not for human use.
  • Brief Description
    SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
  • Description
    SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μ M at VEGFR2, FGFR1, PDGFR β and EGFR respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SU5402 | SU-5402 | SU 5402
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    FGFR1| PDGFRβ| VEGFR2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    215543-92-3
  • Formula Weight
    296.32
  • Molecular Formula
    C17H16N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 30 mg/mL; 101.24 mM
  • SMILES
    CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O
  • Chemical Name
    (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid.

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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