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SC-560
CAS No. 188817-13-2
SC-560( SC-560 | SC 560 | SC560 )
Catalog No. M17399 CAS No. 188817-13-2
SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 49 | In Stock |
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| 10MG | 88 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 234 | In Stock |
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| 100MG | 300 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSC-560
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NoteResearch use only, not for human use.
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Brief DescriptionSC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
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DescriptionSC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
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In Vitro——
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In Vivo——
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SynonymsSC-560 | SC 560 | SC560
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PathwayOthers
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TargetOther Targets
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RecptorCOX-1| COX-2
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Research AreaCancer|Inflammation/Immunology
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Indication——
Chemical Information
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CAS Number188817-13-2
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Formula Weight352.74
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Molecular FormulaC17H12ClF3N2O
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
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SMILESCOc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
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Chemical Name5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
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