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6-CFDA N-succinimidyl ester
CAS No. 150206-15-8
6-CFDA N-succinimidyl ester( —— )
Catalog No. M17327 CAS No. 150206-15-8
The succinimidyl ester group is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mammalian cells and bacteria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 58 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 147 | In Stock |
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| 50MG | 253 | In Stock |
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| 100MG | 373 | In Stock |
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| 200MG | 528 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name6-CFDA N-succinimidyl ester
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NoteResearch use only, not for human use.
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Brief DescriptionThe succinimidyl ester group is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mammalian cells and bacteria.
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DescriptionThe succinimidyl ester group is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mammalian cells and bacteria. Used in combination with several cell permeabilizers as an effective, nondestructive fluorescencent stain to quickly detect bacterial cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetJNK
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number150206-15-8
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Formula Weight557.47
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Molecular FormulaC29H19NO11
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(=O)Oc5cc6Oc1cc(ccc1C3(OC(=O)c2ccc(cc23)C(=O)ON4C(=O)CCC4=O)c6cc5)OC(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Tanzisertib
Tanzisertib (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Tanzisertib (CC-930) inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM)[1] and it blocks the JNK pathway that is activated by pro-fibrotic cytokines in systemic sclerosis.
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AS601245
AS601245, an anti-Inflammatory JNK inhibitor, and Clofibrate have a synergistic effect in inducing cell responses and in affecting the gene expression profile in CaCo-2 colon cancer cells .
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