Mutant EGFR inhibitor( MDK3627 | MDK 3627 | Mutant EGFR inhibitor )

Catalog No. M17288 CAS No. 1421373-62-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Mutant EGFR inhibitor
Note

Research use only, not for human use.
Brief Description

Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.
Description

MDK3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR inhibitor(L858R activating mutant.
In Vitro

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In Vivo

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Synonyms

MDK3627 | MDK 3627 | Mutant EGFR inhibitor
Pathway

Others
Target

Platelet aggregation
Recptor

EGFR (mutant)
Research Area

Cancer
Indication

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CAS Number

1421373-62-7
Formula Weight

520.03
Molecular Formula

C27H30ClN7O2
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 50 mg/mL. 96.15 mM; H2O : < 0.1 mg/mL
SMILES

COc1c(Nc2ncc(Cl)c(n2)c2c[nH]c3ccccc23)cc(NC(=O)C=C)c(c1)N(C)CCN(C)C
Chemical Name

(Z)-N-(5-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylimidic acid