Cart
sales@molnova.com
Miriplatin
CAS No. 141977-79-9
Miriplatin( SM-11355 )
Catalog No. M17286 CAS No. 141977-79-9
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 32 | In Stock |
|
| 25MG | 48 | In Stock |
|
| 50MG | 65 | In Stock |
|
| 100MG | 101 | In Stock |
|
| 200MG | 148 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMiriplatin
-
NoteResearch use only, not for human use.
-
Brief DescriptionMiriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
-
DescriptionMiriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
-
In VitroMiriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
-
In VivoMiriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
-
SynonymsSM-11355
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorDNA Alkylator/Crosslinker
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number141977-79-9
-
Formula Weight764
-
Molecular FormulaC34H68N2O4Pt
-
Purity>98% (HPLC)
-
SolubilityDMF : < 1 mg/mL
-
SMILES[Pt+2].O=C([O-])CCCCCCCCCCCCC.N[C@@H]1CCCC[C@H]1N.[O-]C(=O)CCCCCCCCCCCCC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ishikawa T, et al. Predictive factor of local recurrence after balloon-occluded TACE with miriplatin (MPT) in hepatocellular carcinoma. PLoS One. 2014 Jul 21;9(7):e103009.
molnova catalog
related products
-
RP-5063
RP-5063 (Brilaroxazine) is a multimodal dopamine and serotonin modulator with partial agonist activity at DA D2, D3, D4, 5-HT1A, and 5-HT2ARs, and antagonist activity at 5-HT2B, 5-HT6 and 5-HT7Rs.
-
Trazpiroben
Trazpiroben (TAK-906) is a selective dopamine D2/D3 receptor antagonist utilized in gastroparesis research.
-
SKF83959
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.
