Miriplatin

CAS No. 141977-79-9

Miriplatin( SM-11355 )

Catalog No. M17286 CAS No. 141977-79-9

Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 51 In Stock
25MG 77 In Stock
50MG 104 In Stock
100MG 164 In Stock
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Biological Information

  • Product Name
    Miriplatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
  • Description
    Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
  • In Vitro
    Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
  • In Vivo
    Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
  • Synonyms
    SM-11355
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    DNA Alkylator/Crosslinker
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    141977-79-9
  • Formula Weight
    764
  • Molecular Formula
    C34H68N2O4Pt
  • Purity
    >98% (HPLC)
  • Solubility
    DMF : < 1 mg/mL
  • SMILES
    [Pt+2].O=C([O-])CCCCCCCCCCCCC.N[C@@H]1CCCC[C@H]1N.[O-]C(=O)CCCCCCCCCCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ishikawa T, et al. Predictive factor of local recurrence after balloon-occluded TACE with miriplatin (MPT) in hepatocellular carcinoma. PLoS One. 2014 Jul 21;9(7):e103009.
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