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Miriplatin
CAS No. 141977-79-9
Miriplatin( SM-11355 )
Catalog No. M17286 CAS No. 141977-79-9
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 32 | In Stock |
|
| 25MG | 48 | In Stock |
|
| 50MG | 65 | In Stock |
|
| 100MG | 101 | In Stock |
|
| 200MG | 148 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMiriplatin
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NoteResearch use only, not for human use.
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Brief DescriptionMiriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
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DescriptionMiriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
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In VitroMiriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
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In VivoMiriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
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SynonymsSM-11355
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorDNA Alkylator/Crosslinker
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number141977-79-9
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Formula Weight764
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Molecular FormulaC34H68N2O4Pt
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Purity>98% (HPLC)
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SolubilityDMF : < 1 mg/mL
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SMILES[Pt+2].O=C([O-])CCCCCCCCCCCCC.N[C@@H]1CCCC[C@H]1N.[O-]C(=O)CCCCCCCCCCCCC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ishikawa T, et al. Predictive factor of local recurrence after balloon-occluded TACE with miriplatin (MPT) in hepatocellular carcinoma. PLoS One. 2014 Jul 21;9(7):e103009.
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