lavendustin C

CAS No. 125697-93-0

lavendustin C( Lavendustin C | HDBA, NSC 666251 )

Catalog No. M17229 CAS No. 125697-93-0

Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 83 In Stock
2MG 50 In Stock
5MG 85 In Stock
10MG 155 In Stock
25MG 349 In Stock
50MG 508 In Stock
100MG 731 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    lavendustin C
  • Note
    Research use only, not for human use.
  • Brief Description
    Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
  • Description
    Lavendustin C, also known as HDBA and NSC 666251, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM.. HDBA inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.
  • In Vitro
    Lavendustin C (Compound 5) shows potent inhibitory activity, and it may be the core structure responsible for inhibition of tyrosine kinase. Lavendustin C (10-150 μM) inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.
  • In Vivo
    ——
  • Synonyms
    Lavendustin C | HDBA, NSC 666251
  • Pathway
    MAPK/ERK Signaling
  • Target
    Raf
  • Recptor
    tyrosine kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    125697-93-0
  • Formula Weight
    275.26
  • Molecular Formula
    C14H13NO5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (363.29 mM)
  • SMILES
    O=C(O)c1cc(NCc2cc(O)ccc2O)ccc1O
  • Chemical Name
    5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nynca A, et al. Domest Anim Endocrinol. 2013 Jan;44(1):10-8
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