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IDE1
CAS No. 1160927-48-9
IDE1( IDE1 | IDE-1 | IDE 1 )
Catalog No. M17158 CAS No. 1160927-48-9
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 246 | In Stock |
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| 50MG | 362 | In Stock |
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| 100MG | 546 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIDE1
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NoteResearch use only, not for human use.
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Brief DescriptionIDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells.
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DescriptionIDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2 (ab145223). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression.
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In Vitro——
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In Vivo——
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SynonymsIDE1 | IDE-1 | IDE 1
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1160927-48-9
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Formula Weight306.3
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Molecular FormulaC15H18N2O5
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 30 mg/mL 97.94 mM
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SMILESc1ccc(c(c1)/C=N/NC(=O)CCCCCC(=O)O)C(=O)O
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Chemical Name7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.
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