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VUF10460
CAS No. 1028327-66-3
VUF10460( —— )
Catalog No. M17121 CAS No. 1028327-66-3
VUF10460 is a non-imidazole histamine H4 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
|
| 5MG | 28 | In Stock |
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| 10MG | 47 | In Stock |
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| 25MG | 93 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | 251 | In Stock |
|
| 200MG | 370 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVUF10460
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NoteResearch use only, not for human use.
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Brief DescriptionVUF10460 is a non-imidazole histamine H4 receptor agonist.
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DescriptionVUF10460 is a non-imidazole histamine H4 receptor agonist.
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In VitroUF10460 binds to rat H3 and H4 receptor with pKi values of 5.75, and 7.46, respectively. VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor.
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In VivoHCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorH4 receptor
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1028327-66-3
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Formula Weight269.35
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Molecular FormulaC15H19N5
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 36 mg/mL 133.66 mM
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SMILESCN1CCN(CC1)c1cc(c2ccccc2)nc(N)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Coruzzi G, et al. Selective histamine H3 and H4 receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach. Eur J Pharmacol. 2011 Nov 1;669(1-3):121-7.
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