GSK3011724A

CAS No. ——

GSK3011724A( DG167 | GSK-3011724A )

Catalog No. M17106 CAS No. ——

GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GSK3011724A
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).
  • Description
    GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM); shows much weaker apparent dissociation constant for both Pks10 and Pks (Kd=1.4 uM); inhibits mycolic acid biosynthesis and shows negligible activity against a panel of unrelated proteins and 18 Gram-positive and Gram-negative bacterial species.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DG167 | GSK-3011724A
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    267.347
  • Molecular Formula
    C12H17N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    N-(1-methyl-1H-indazol-6-yl)butane-1-sulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kumar P, et al. MBio. 2018 Dec 18;9(6). pii: e02101-17. 2. Abrahams KA, et al. Nat Commun. 2016 Sep 1;7:12581.
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