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CN427
CAS No. ——
CN427( CN-427 | CN 427 )
Catalog No. M17055 CAS No. ——
CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCN427
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NoteResearch use only, not for human use.
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Brief DescriptionCN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
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DescriptionCN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
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In Vitro——
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In Vivo——
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SynonymsCN-427 | CN 427
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight496.571
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Molecular FormulaC28H28N6O3
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Purity>98% (HPLC)
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Solubility——
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SMILESOCCN1N=CC(C2=NC(N3C(C4=CC=CC=C4)COCC3)=C5C=C(C6=C(C)ON=C6C)C=CC5=N2)=C1
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Chemical Name2-(4-(6-(3,5-dimethylisoxazol-4-yl)-4-(3-phenylmorpholino)quinazolin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yang SM, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488.
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