BTT-369( BTT 369 | BTT 369 )

Catalog No. M17024 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

BTT-369
Note

Research use only, not for human use.
Brief Description

BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor.
Description

BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction with Ki of 2.0 uM in FP assays; decreases trafficking of CaV2.2 channels to the plasma membrane and modulates the functions of the channel, suppresses pain responses in rodent neuropathic pain models; BTT-369 (BTT369) is a cell-permeable derivative of BTT-266.
In Vitro

——
In Vivo

——
Synonyms

BTT 369 | BTT 369
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel
Research Area

——
Indication

——

CAS Number

——
Formula Weight

580.652
Molecular Formula

C34H28N8O2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

(3-(1H-tetrazol-5-yl)phenyl)(5-(4-methoxyphenyl)-1'-phenyl-3'-(p-tolyl)-3,4-dihydro-1'H,2H-[3,4'-bipyrazol]-2-yl)methanone

1. Chen X, et al. Proc Natl Acad Sci U S A. 2018 Oct 24. pii: 201813157.

Calculator

molnova catalog