Cart
sales@molnova.com
BL-AD008
CAS No. ——
BL-AD008( BL-AD 008 )
Catalog No. M17014 CAS No. ——
BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBL-AD008
-
NoteResearch use only, not for human use.
-
Brief DescriptionBL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.
-
DescriptionBL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK; demonstrates remarkable anti-proliferative activities toward cervical cancer cells and could induce apoptosis by death-receptor and mitochondrial pathways; also shows anti-tumor activities and induces apoptosis by targeting AMPK/ZIPK in vivo.
-
In Vitro——
-
In Vivo——
-
SynonymsBL-AD 008
-
PathwayMembrane Transporter/Ion Channel
-
TargetAMPK
-
RecptorAMPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight501.045
-
Molecular FormulaC28H25ClN4OS
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(Z)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-3-benzylidene-6-chloroindolin-2-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fu L, et al. Oncotarget. 2015 Apr 10;6(10):8071-88.
molnova catalog
related products
-
AMPK activator 4
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I.
-
ZLN-024
A novel AMPK allosteric activator that has no effect on mitochondrial function or the ADP/ATP ratio; directly activate recombinant AMPK α1β1γ1 and its homologue α2β1γ1 with EC50 of 0.42 uM and 0.95 uM, respectively.
-
ZLN 024 hydrochlorid...
ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).
