Cart
sales@molnova.com
PKCiota-IN-51
CAS No. ——
PKCiota-IN-51( —— )
Catalog No. M16985 CAS No. ——
PKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM。
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePKCiota-IN-51
-
NoteResearch use only, not for human use.
-
Brief DescriptionPKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM。
-
DescriptionPKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM, >15-fold selectivity over PKC-α and PKC-β; inhibits PKC-ι on the phosphorylation of substrate ECT2 in HCCLM3 cells with IC50 of 3.3 uM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetPKC
-
RecptorPKC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight427.483
-
Molecular FormulaC25H22FN5O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name7-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazolo[1,5-a]pyridin-3-yl)-3-(fluoromethyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kwiatkowski J, et al. J Med Chem. 2018 May 4. doi: 10.1021/acs.jmedchem.8b00060.
molnova catalog
related products
-
[Ala113]-MBP (104-11...
Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).
-
Cholesterol 3-Sulfat...
Cholesterol sulfate is a sterol sulfate in human plasma. It is a component of cell membrane and has a regulatory function. It also activates multiple protein kinase C (PKC) iso-enzymes especially the ε η and ζ isoforms.
-
OSU-2S
A non-immunosuppressive FTY720 analogue, PKCδ activator with higher antiproliferative potency.
