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CAMKK2 inhibitor 4t
CAS No. ——
CAMKK2 inhibitor 4t( —— )
Catalog No. M16972 CAS No. ——
CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCAMKK2 inhibitor 4t
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NoteResearch use only, not for human use.
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Brief DescriptionCAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.
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DescriptionCAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5; potently inhibits AMPK phosphorylation in a hypothalamus-derived cell line with pIC50 of 6.3; reduces food intake in rodent models.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetCaMK
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RecptorCaMK
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight480.612
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Molecular FormulaC30H32N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-isopropyl-4-(2-(2-methyl-4-(2-morpholinoethoxy)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Price DJ, et al. Bioorg Med Chem Lett. 2018 Apr 5. pii: S0960-894X(18)30223-3.
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