Ischemin sodium( —— )

Catalog No. M16925 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Ischemin sodium
Note

Research use only, not for human use.
Brief Description

A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Description

A cell permeable CBP bromodomain inhibitor with Kd of 19 uM; inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity; protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Bromodomain
Recptor

Bromodomain
Research Area

——
Indication

——

CAS Number

——
Formula Weight

357.36
Molecular Formula

C15H16N3O4SNa
Purity

>98% (HPLC)
Solubility

——
SMILES

O=S(C1=CC(/N=N/C2=CC(C)=C(O)C=C2N)=C(C)C=C1C)([O-])=O.[Na+]
Chemical Name

5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt

1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.

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