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FV-100
CAS No. 956483-03-7
FV-100( Valnivudine | FV100 | CF-1743 )
Catalog No. M16827 CAS No. 956483-03-7
FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 148 | In Stock |
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| 10MG | 248 | In Stock |
|
| 25MG | 386 | In Stock |
|
| 50MG | 500 | In Stock |
|
| 100MG | 684 | In Stock |
|
| 200MG | 905 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFV-100
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NoteResearch use only, not for human use.
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Brief DescriptionFV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.
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DescriptionFV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.HSV Infection Phase 3 Clinical.
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In VitroFV-100 is intensely fluorescent when illuminated by wavelengths of 340-380 nm.FV-100 (1 h) produces a different distribution in HeLa cells.
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In VivoFV-100 (50-500 mg/kg; p.o.) does not induce biologically relevant respiratory changes or any apparent neuropharmacological effects in rats.
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SynonymsValnivudine | FV100 | CF-1743
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PathwayMicrobiology/Virology
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TargetHSV
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RecptorHSV
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Research AreaInfection
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IndicationHSV Infection
Chemical Information
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CAS Number956483-03-7
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Formula Weight548.077
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Molecular FormulaC28H38ClN3O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (187.25 mM)
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SMILESCCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)C4CC(C(O4)COC(=O)C(C(C)C)N)O.Cl
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Chemical Name((2R,3S,5R)-3-hydroxy-5-(2-oxo-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-3(2H)-yl)tetrahydrofuran-2-yl)methyl (S)-3-amino-4-methylpentanoate hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. McGuigan C, et al. J Antimicrob Chemother. 2007 Dec;60(6):1316-30.
2. Pentikis HS, et al. Antimicrob Agents Chemother. 2011 Jun;55(6):2847-54.
3. Migliore M. Antivir Chem Chemother. 2010 Jan 5;20(3):107-15.
4. Tyring SK, et al. J Med Virol. 2017 Jul;89(7):1255-1264.
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