Butyl 4-aminobenzoate

Research use only, not for human use.

Butamben is a long-duration local anesthetic used for the treatment of chronic pain.

Butamben is a long-duration local anesthetic used for the treatment of chronic pain.(In Vitro):Butamben (500 μM) blocks 90% of the control barium current, and this level is reached within 4 min in PC12 cells.Butamben (100 μM; 2-10 min) increases the inactivation of the fast Na+ channels, but not of the slow Na+ channels.(In Vivo):Butamben (0.5-50 mM; the distal portion of the tail was immersed for 2 min) has an S-shape dose-dependent analgesic activity in the radiant heat tail-flick assay of mice.

Butamben (500 μM) blocks 90% of the control barium current, and this level is reached within 4 min in PC12 cells.Butamben (100 μM; 2-10 min) increases the inactivation of the fast Na+ channels, but not of the slow Na+ channels.

Butamben (0.5-50 mM; the distal portion of the tail was immersed for 2 min) has an S-shape dose-dependent analgesic activity in the radiant heat tail-flick assay of mice.

Butamben, Butanylcaine, Butesin, Zyljectin, Butoform, Planoform

Membrane Transporter/Ion Channel

Sodium Channel

Sodium Channel

Neurological Disease

——

94-25-7

193.24

C11H15NO2

>98% (HPLC)

DMSO: 10 mM

O=C(OCCCC)C1=CC=C(N)C=C1

butyl 4-aminobenzoate

(-20℃)

With Ice Pack

≥ 2 years