Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - FiVe1

FiVe1

CAS No. 932359-76-7

FiVe1( FiVe1 | FiVe 1 | FiVe-1 )

Catalog No. M16670 CAS No. 932359-76-7

FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	718	Get Quote
10MG	981	Get Quote
25MG	1485	Get Quote
50MG	2007	Get Quote
100MG	2637	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

FiVe1
Note

Research use only, not for human use.
Brief Description

FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase.
Description

FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells; selectively and irreversibly inhibits the growth of mesenchymally transformed breast cancer cells ( FOXC2-HMLER cells IC50=234 nM) and soft tissue sarcomas of diverse histological subtypes.
In Vitro

——
In Vivo

——
Synonyms

FiVe1 | FiVe 1 | FiVe-1
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Microtubule/Tubulin
Recptor

Microtubule/Tubulin
Research Area

——
Indication

——

Chemical Information

CAS Number

932359-76-7
Formula Weight

359.254
Molecular Formula

C18H16Cl2N4
Purity

>98% (HPLC)
Solubility

——
SMILES

ClC1=CC(N2CCN(C3=C4C=CC=C(Cl)C4=NN=C3)CC2)=CC=C1
Chemical Name

8-chloro-4-(4-(3-chlorophenyl)piperazin-1-yl)cinnoline

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Isosorbide Mononitra...

Isosorbide mononitrate is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.
LR-510444

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.
Vinflunine ditartrat...

Vinflunine ditartrate is the first fluorinated microtubule inhibitor belonging to the Vinca alkaloids family. Vinflunine ditartrate has anti-angiogenic, vascular-disrupting and anti-metastatic activities.

Sign In Join Free