Radotinib( IY-5511 )

Catalog No. M16635 CAS No. 926037-48-1

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Product Name

Radotinib
Note

Research use only, not for human use.
Brief Description

Radotinib, and sometimes referred to by its investigational name IY5511.
Description

Radotinib, and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other tyrosine kinase Bcr-Abl inhibitors.
In Vitro

——
In Vivo

——
Synonyms

IY-5511
Pathway

Tyrosine Kinase
Target

Bcr-Abl
Recptor

Bcr-Abl1
Research Area

Cancer
Indication

——

CAS Number

926037-48-1
Formula Weight

530.5
Molecular Formula

C27H21F3N8O
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

CC1=CN(C=N1)C1=CC(NC(=O)C2=CC(NC3=NC=CC(=N3)C3=NC=CN=C3)=C(C)C=C2)=CC(=C1)C(F)(F)F
Chemical Name

——

1.Heo SK, et al. PLoS One. 2015 Jun 12;10(6):e0129853.

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