Cart
sales@molnova.com
CZC-8004
CAS No. 916603-07-1
CZC-8004( CZC 8004 | CZC8004 | Dianilinopyrimidine-01 )
Catalog No. M16584 CAS No. 916603-07-1
CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
|
| 5MG | 85 | In Stock |
|
| 10MG | 140 | In Stock |
|
| 25MG | 297 | In Stock |
|
| 50MG | 435 | In Stock |
|
| 100MG | 626 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCZC-8004
-
NoteResearch use only, not for human use.
-
Brief DescriptionCZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases.
-
DescriptionCZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations.
-
In Vitro——
-
In Vivo——
-
SynonymsCZC 8004 | CZC8004 | Dianilinopyrimidine-01
-
PathwayAngiogenesis
-
TargetBcr-Abl
-
RecptorBcr-Abl
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number916603-07-1
-
Formula Weight309.3
-
Molecular FormulaC17H16FN5
-
Purity>98% (HPLC)
-
SolubilityDMSO : 77.5 mg/mL 250.53 mM
-
SMILESC1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
-
Chemical NameN2-?[4-?(aminomethyl)?phenyl]?-?5-?fluoro-?N4-?phenyl-2,?4-?pyrimidinediamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Klutchko SR, et al. J Med Chem. 1998 Aug 13;41(17):3276-92.
molnova catalog
related products
-
Vodobatinib
Vodobatinib is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
-
XL228
XL228 is an inhibitor of multi-targeted tyrosine kinase.
-
AKE-72
AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.
