CZC-8004

CAS No. 916603-07-1

CZC-8004( CZC 8004 | CZC8004 | Dianilinopyrimidine-01 )

Catalog No. M16584 CAS No. 916603-07-1

CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 85 In Stock
10MG 140 In Stock
25MG 297 In Stock
50MG 435 In Stock
100MG 626 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CZC-8004
  • Note
    Research use only, not for human use.
  • Brief Description
    CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases.
  • Description
    CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CZC 8004 | CZC8004 | Dianilinopyrimidine-01
  • Pathway
    Angiogenesis
  • Target
    Bcr-Abl
  • Recptor
    Bcr-Abl
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    916603-07-1
  • Formula Weight
    309.3
  • Molecular Formula
    C17H16FN5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 77.5 mg/mL 250.53 mM
  • SMILES
    C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
  • Chemical Name
    N2-?[4-?(aminomethyl)?phenyl]?-?5-?fluoro-?N4-?phenyl-2,?4-?pyrimidinediamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Klutchko SR, et al. J Med Chem. 1998 Aug 13;41(17):3276-92.
molnova catalog
related products
  • AKE-72

    AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.

  • Gypsogenin

    Gypsogenin is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.

  • PPY A

    PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase (IC50 of 9 and 20 nM, respectively).PPY A also inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl genetically transformed cells.