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NVP-BDZ 824
CAS No. 916306-04-2
NVP-BDZ 824( NVP-BDZ824 | BDZ 824 )
Catalog No. M16580 CAS No. 916306-04-2
A potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNVP-BDZ 824
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.
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DescriptionA potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.
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In Vitro——
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In Vivo——
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SynonymsNVP-BDZ824 | BDZ 824
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number916306-04-2
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Formula Weight442.563
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Molecular FormulaC27H30N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(6aR,9R)-N9,N9-diethyl-N7-(o-tolyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Thoma G, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6185-8.
2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.
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