Cart
sales@molnova.com
T1551
CAS No. 913691-90-4
T1551( T 1551 | T-1551 )
Catalog No. M16565 CAS No. 913691-90-4
T1551 is a novel, potent and specific PRMT5 inhibitor with IC50 of 34.1 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameT1551
-
NoteResearch use only, not for human use.
-
Brief DescriptionT1551 is a novel, potent and specific PRMT5 inhibitor with IC50 of 34.1 uM.
-
DescriptionT1551 is a novel, potent and specific PRMT5 inhibitor with IC50 of 34.1 uM, exhibits anti-proliferation on A549 cell with IC50 of 11.2 uM; reduces symmetric dimethylation level of H4R3, downregulates the protein expressions of two target genes of PRMT5, FGFR3, and eIF4E, and inhibits the activation of PI3K/AKT/mTOR and ERK signaling.
-
In Vitro——
-
In Vivo——
-
SynonymsT 1551 | T-1551
-
PathwayChromatin/Epigenetic
-
TargetHMTase
-
RecptorHMTase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number913691-90-4
-
Formula Weight302.401
-
Molecular FormulaC16H24N5O+
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCCC[NH+]=C(N)NN=CC1=CNC2=C1C=C(C=C2)CO
-
Chemical NameN-((E)-amino(2-(((Z)-5-(hydroxymethyl)-3H-indol-3-ylidene)methyl)hydrazinyl)methylene)pentan-1-aminium
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang Q, et al. Front Pharmacol. 2018 Mar 1;9:173.
molnova catalog
related products
-
MM-102 trifluoroacet...
A high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
-
CARM1-IN-7g
CARM1-IN-7g is a potent, selective coactivator-associated arginine methyltransferase 1 (CARM1) with IC50 of 8.6 uM.
-
WDR5-MLL1 inhibitor
WDR5-MLL1 inhibitor is a novel potent inhibitor of WDR5-MLL1 interaction, binds to WDR5 with Kd of 1 nM.
