Bicalutamide
CAS No. 90357-06-5
Bicalutamide( ICI 176334 | ZD 176334 )
Catalog No. M16494 CAS No. 90357-06-5
Bicalutamide is an oral non-steroidal anti-androgen for prostate Y.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 29 | In Stock |
|
| 100MG | 41 | In Stock |
|
| 200MG | 48 | In Stock |
|
| 500MG | 61 | In Stock |
|
| 1G | 77 | In Stock |
|
Biological Information
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Product NameBicalutamide
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NoteResearch use only, not for human use.
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Brief DescriptionBicalutamide is an oral non-steroidal anti-androgen for prostate Y.
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DescriptionBicalutamide is an oral non-steroidal anti-androgen for prostate Y. It binds to the androgen receptor.
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In Vitro——
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In VivoAnimal Model:Castrate male mice, bearing LNCaP/AR(cs) xenograft tumors Dosage:10 mg/kg Administration:Oral gavage, daily, for 28 daysResult:Inhibited tumors growth.
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SynonymsICI 176334 | ZD 176334
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number90357-06-5
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Formula Weight430.37
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Molecular FormulaC18H14F4N2O4S
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Purity>98% (HPLC)
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SolubilityEthanol: 5 mg/mL (11.61 mM); DMSO: 86 mg/mL (199.82 mM)
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SMILESO=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)CS(=O)(C2=CC=C(F)C=C2)=O
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Chemical NameN-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AS-601811
AS-601811 is a steroidal 5α-reductase inhibitor and androgen receptor modulator used to study hair loss and acne.
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Dimethylcurcumin
Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.Dimethylcurcumin is able to degrade fAR and AR3 in a dose-dependent manner in various human PCa cells. Dimethylcurcumin can also effectively suppress AR-targeted genes in CWR22Rv1-fARKD cells.
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LGD-3303
LGD-3303 is an orally available, brain-penetrant nonsteroidal selective androgen receptor modulator (SARM) that that shows little or no cross-reactivity with related nuclear receptors.
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