c-FMS-IN-8

CAS No. 885704-21-2

c-FMS-IN-8( —— )

Catalog No. M16411 CAS No. 885704-21-2

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 112 In Stock
5MG 107 In Stock
10MG 164 In Stock
25MG 278 In Stock
50MG 369 In Stock
100MG 540 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    c-FMS-IN-8
  • Note
    Research use only, not for human use.
  • Brief Description
    c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.
  • Description
    c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    CSF1R
  • Recptor
    CSF1R
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    885704-21-2
  • Formula Weight
    406.5239
  • Molecular Formula
    C23H30N6O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO
  • SMILES
    CC1CCN(CC1)C2=C(C=CC(=C2)N3CCN(CC3)C)NC(=O)C4=CC(=CN4)C#N
  • Chemical Name
    1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Illig CR, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8. 2. Meegalla SK, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3632-7.
molnova catalog
related products
  • Otilimab

    Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF).

  • AZD7507

    AZD7507 (AZD-7507) is a potent, selective, orally available CSF-1R (c-FMS) with IC50 of 32 nM.

  • CSF1R-IN-22

    CSF1R-IN-22 is a potent, cellular active and orally bioavailable CSF1R inhibitor with IC50 of 0.5 nM.