c-FMS-IN-8

CAS No. 885704-21-2

c-FMS-IN-8( —— )

Catalog No. M16411 CAS No. 885704-21-2

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 170 Get Quote
10MG 260 Get Quote
25MG 440 Get Quote
50MG 617 Get Quote
100MG 872 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    c-FMS-IN-8
  • Note
    Research use only, not for human use.
  • Brief Description
    c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.
  • Description
    c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    CSF1R
  • Recptor
    CSF1R
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    885704-21-2
  • Formula Weight
    406.5239
  • Molecular Formula
    C23H30N6O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO
  • SMILES
    CC1CCN(CC1)C2=C(C=CC(=C2)N3CCN(CC3)C)NC(=O)C4=CC(=CN4)C#N
  • Chemical Name
    1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Illig CR, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8. 2. Meegalla SK, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3632-7.
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