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Home - Products - Microbiology/Virology - HCV - BI 207524

BI 207524

CAS No. 874675-53-3

BI 207524( BI207524 )

Catalog No. M16359 CAS No. 874675-53-3

BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BI 207524
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.
  • Description
    BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BI207524
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    874675-53-3
  • Formula Weight
    642.153
  • Molecular Formula
    C35H36ClN5O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-3-{4-[(1-{[2-(5-Chloropyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carbonyl]-amino}-cyclobutanecarbonyl)-amino]-2-ethoxy-phenyl}-acrylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beaulieu PL, et al. J Med Chem. 2014 Dec 11;57(23):10130-43. 2. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1135-9. 3. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1140-5.
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