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INCB13739
CAS No. 872506-67-7
INCB13739( INCB-13739 | INCB 13739 )
Catalog No. M16343 CAS No. 872506-67-7
INCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 387 | Get Quote |
|
| 10MG | 572 | Get Quote |
|
| 25MG | 888 | Get Quote |
|
| 50MG | 1224 | Get Quote |
|
| 100MG | 1647 | Get Quote |
|
| 500MG | 3312 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameINCB13739
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NoteResearch use only, not for human use.
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Brief DescriptionINCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.
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DescriptionINCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.Diabetes Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsINCB-13739 | INCB 13739
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PathwayMetabolic Enzyme/Protease
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Target11β-HSD
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Recptor11β-HSD
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number872506-67-7
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Formula Weight398.946
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Molecular FormulaC19H27ClN2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(3S)-1-[(3-Chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-3-piperidinecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rosenstock J, et al. Diabetes Care. 2010 Jul;33(7):1516-22.
2. Ge R, et al. Curr Med Chem. 2010;17(5):412-22.
3. Anagnostis P, et al. Metabolism. 2013 Jan;62(1):21-33.
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