Torezolid( TR-701 | tedizolid )

Catalog No. M16213 CAS No. 856866-72-3

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Product Name

Torezolid
Note

Research use only, not for human use.
Brief Description

Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.
Description

Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.(In Vitro):Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.(In Vivo):For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.
In Vitro

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In Vivo

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Synonyms

TR-701 | tedizolid
Pathway

Metabolic Enzyme/Protease
Target

MAO
Recptor

MAO-A| MAO-B
Research Area

Infection
Indication

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CAS Number

856866-72-3
Formula Weight

370.34
Molecular Formula

C17H15FN6O3
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

O=C1O[C@@H](CO)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2
Chemical Name

(5R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

1.Choi S, et al. Antimicrob Agents ChemOthers. 2012 Jun 19.

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