Cart
sales@molnova.com
Trofinetide
CAS No. 853400-76-7
Trofinetide( NNZ 2566 )
Catalog No. M16197 CAS No. 853400-76-7
Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 67 | In Stock |
|
| 10MG | 107 | In Stock |
|
| 25MG | 231 | In Stock |
|
| 50MG | 361 | In Stock |
|
| 100MG | 576 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTrofinetide
-
NoteResearch use only, not for human use.
-
Brief DescriptionTrofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
-
DescriptionTrofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration; improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury; significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.Other Indication Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsNNZ 2566
-
PathwayOthers
-
TargetOther Targets
-
RecptorOther Targets
-
Research AreaOther Indications
-
IndicationOther Disease
Chemical Information
-
CAS Number853400-76-7
-
Formula Weight315.322
-
Molecular FormulaC13H21N3O6
-
Purity>98% (HPLC)
-
SolubilityH2O : ≥ 50 mg/mL 158.57 mM
-
SMILESO=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O
-
Chemical Name((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
6,7-Dimethoxy-2-[2-(...
NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects.
-
Prolactin-Releasing ...
Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor.
-
Isoscoparin 7-O-gluc...
Isoscoparin-7-O-glucoside is a flavonoid compound found in barley leaves. The total phenolic content (TPC) of isoscoparin-7-O-glucoside is positively correlated with COX-2 inhibitory activity, indicating anti-inflammatory activity. Isoscoparin-7-O-glucoside can be used in the study of inflammation.
