Falecalcitriol( Ro 23-4194 | Ro-23-4194 | Ro23-4194 | ST 630 | ST-630 | ST630 | Flocalcitriol | Hornel, Fulstan | Falecalcitriol )

Catalog No. M16107 CAS No. 83805-11-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Falecalcitriol
Note

Research use only, not for human use.
Brief Description

A hexafluorinated analogue of 1,25(OH)2 vitamin D3, has been reported to be several times more potent than the parent compound regarding some vitamin D actions.
Description

A hexafluorinated analogue of 1,25(OH)2 vitamin D3, has been reported to be several times more potent than the parent compound regarding some vitamin D actions.Hyperparathyroidism Approved.
In Vitro

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In Vivo

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Synonyms

Ro 23-4194 | Ro-23-4194 | Ro23-4194 | ST 630 | ST-630 | ST630 | Flocalcitriol | Hornel, Fulstan | Falecalcitriol
Pathway

Metabolic Enzyme/Protease
Target

Vitamin
Recptor

Vitamin
Research Area

Endocrinology
Indication

Hyperparathyroidism

CAS Number

83805-11-2
Formula Weight

524.5792
Molecular Formula

C27H38F6O3
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

C[C@H](CCCC(C(F)(F)F)(O)C(F)(F)F)[C@H]([C@]1(CCC/2)C)CC[C@@]1([H])C2=C\C=C3C[C@H](O)C[C@@H](O)C\3=C
Chemical Name

1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[1-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,4S,5Z)-

1. Komuro S, et al. Xenobiotica. 1999 Jun;29(6):603-13. 2. Akiba T, et al. Am J Kidney Dis. 1998 Aug;32(2):238-46.

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