Bambuterol hydrochloride( KWD-2183 )

Catalog No. M16044 CAS No. 81732-46-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Bambuterol hydrochloride
Note

Research use only, not for human use.
Brief Description

A long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma.
Description

A long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; also is a prodrug of terbutaline.Asthma Approved(In Vitro):Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
In Vitro

Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
In Vivo

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Synonyms

KWD-2183
Pathway

GPCR/G Protein
Target

Adrenergic Receptor
Recptor

AChR|β-adrenergicreceptor
Research Area

Inflammation/Immunology
Indication

Asthma

CAS Number

81732-46-9
Formula Weight

403.9009
Molecular Formula

C18H30ClN3O5
Purity

>98% (HPLC)
Solubility

DMSO: < 7.6 mg/mL
SMILES

CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl
Chemical Name

Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1)