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Capitrol

CAS No. 773-76-2

Capitrol( chloroxine hydrofluoride | chlorquinol | dichlorohydroxyquinoline | dichloroquine | quixalin )

Catalog No. M15923 CAS No. 773-76-2

Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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1 mL x 10 mM in DMSO 28 In Stock
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Biological Information

  • Product Name
    Capitrol
  • Note
    Research use only, not for human use.
  • Brief Description
    Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
  • Description
    Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.(In Vitro):By using the Jouyban-Acree model, the Chloroxine solubility is well correlated obtaining RAD values lower than 3.64% and RMSD values lower than 8.82 × 10 6. Chloroxine is preferentially solvated by water for the studied mixtures in water-rich compositions; while within intermediate and co-solvent-rich compositions, Chloroxine is preferentially solvated by DMSO (DMF, NMP or 1,4-dioxane) in DMSO (DMF, NMP or 1,4-dioxane) + water mixtures. It is shown that the change in solvent-solvent interaction energy accounted by cavity term governed the solubility variation of Chloroxine in all aqueous mixtures.
  • In Vitro
    By using the Jouyban-Acree model, the Chloroxine solubility is well correlated obtaining RAD values lower than 3.64% and RMSD values lower than 8.82?×?10?6. Chloroxine is preferentially solvated by water for the studied mixtures in water-rich compositions; while within intermediate and co-solvent-rich compositions, Chloroxine is preferentially solvated by DMSO (DMF, NMP or 1,4-dioxane) in DMSO (DMF, NMP or 1,4-dioxane)?+?water mixtures. It is shown that the change in solvent-solvent interaction energy accounted by cavity term governed the solubility variation of Chloroxine in all aqueous mixtures.
  • In Vivo
    ——
  • Synonyms
    chloroxine hydrofluoride | chlorquinol | dichlorohydroxyquinoline | dichloroquine | quixalin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    773-76-2
  • Formula Weight
    214.05
  • Molecular Formula
    C9H5Cl2NO
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 43 mg/mL (200.88 mM)
  • SMILES
    C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1
  • Chemical Name
    5,7-dichloroquinolin-8-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Malaveille C, et al. IARC Sci Publ. 1991;(115):261-6.
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