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Chidamide
CAS No. 743420-02-2
Chidamide( CS055 | CS-055 | CS 055 | HBI8000 | HBI 8000 | HBI-8000 | Chidamide | Tucidinostat )
Catalog No. M15838 CAS No. 743420-02-2
Chidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
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| 2MG | 75 | In Stock |
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| 5MG | 132 | In Stock |
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| 10MG | 227 | In Stock |
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| 25MG | 453 | In Stock |
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| 50MG | 649 | In Stock |
|
| 100MG | 923 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameChidamide
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NoteResearch use only, not for human use.
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Brief DescriptionChidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM).
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DescriptionChidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM).
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In Vitro——
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In Vivo——
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SynonymsCS055 | CS-055 | CS 055 | HBI8000 | HBI 8000 | HBI-8000 | Chidamide | Tucidinostat
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC1| HDAC2| HDAC3| HDAC8
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number743420-02-2
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Formula Weight390.41
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Molecular FormulaC22H19FN4O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(NC1=CC(F)=CC=C1N)C2=CC=C(CNC(/C=C/C3=CC=CN=C3)=O)C=C2
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Chemical Name(E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. L, et al. Biochem Biophys Res Commun. 2010 Feb 5;392(2):190-5.
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