Cart
sales@molnova.com
OSU-03013
CAS No. 742112-34-1
OSU-03013( OSU 03013 | OSU03013 )
Catalog No. M15835 CAS No. 742112-34-1
OSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameOSU-03013
-
NoteResearch use only, not for human use.
-
Brief DescriptionOSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
-
DescriptionOSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM; induces apoptosis in PC-3 cells at low microM range, causes Akt dephosphorylation and inhibition of p70 S6 kinase activity; displays cytotocixity against a panel of 60 cell lines with mean GI50 of 3 uM.
-
In Vitro——
-
In Vivo——
-
SynonymsOSU 03013 | OSU03013
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPDK
-
RecptorPDK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number742112-34-1
-
Formula Weight445.449
-
Molecular FormulaC25H18F3N5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)N=C(N)N)C(F)(F)F
-
Chemical Name4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl-guanidine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Baryawno N, et al. Cancer Res. 2010 Jan 1;70(1):266-76.
molnova catalog
related products
-
PS 210
PS 210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1.
-
VER-246608
VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase.
-
BX-320
BX-320 is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 30 nM.
