Amlexanox( AA 673 | CHX 3673 | Elics )

Catalog No. M15611 CAS No. 68302-57-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Amlexanox
Note

Research use only, not for human use.
Brief Description

Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
Description

Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
In Vitro

——
In Vivo

——
Synonyms

AA 673 | CHX 3673 | Elics
Pathway

Angiogenesis
Target

FGFR
Recptor

FGFR1| IL-3| Protein S100-P
Research Area

Inflammation/Immunology
Indication

——

CAS Number

68302-57-8
Formula Weight

298.29
Molecular Formula

C16H14N2O4
Purity

>98% (HPLC)
Solubility

DMSO: 100 mM
SMILES

CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
Chemical Name

2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid

1. Shishibori T, et al. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9.

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