DL-Mevalonolactone( DL-Mevalonic Acid Lactone | (±)-Mevalonolactone | NSC 90804 )

Catalog No. M15570 CAS No. 674-26-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

DL-Mevalonolactone
Note

Research use only, not for human use.
Brief Description

Mevalonic acid is very soluble in water and polar organic solvents.
Description

Mevalonic acid is very soluble in water and polar organic solvents. It exists in equilibrium with its lactone form, called mevalonolactone, that is formed by internal condensation of its terminal alcohol and carboxylic acid functional groups.
In Vitro

Real Time qPCR Cell Line:U87-MG Concentration:0.1-1 mM Incubation Time:72 h Result:Increased SOD, HemeOX and IL1B expression
In Vivo

Animal Model:C57BL/6 mice with cerivastatin/simvastatin induced myopathy Dosage:200 mg/kg Administration:oral gavage Result:Increased muschle strength and endurance in hanging wire and grip tests.
Synonyms

DL-Mevalonic Acid Lactone | (±)-Mevalonolactone | NSC 90804
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1.Endo A, et al. J Lipid Res. 1992 Nov; 33(11):1569-82.

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