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(±)-U-50488 hydrochloride
CAS No. 67197-96-0
(±)-U-50488 hydrochloride( U50488 | U-50488 )
Catalog No. M15564 CAS No. 67197-96-0
A potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1426 | Get Quote |
|
| 100MG | 2139 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(±)-U-50488 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects.
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DescriptionA potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects; shows analgesic, diuretic and antitussive effects, and reverses the memory impairment produced by anticholinergic drugs in vivo.Anxiety Discontinued.
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In Vitro(±)-U-50488 is a racemic mixture of (+)-Trans-(1R,2R)-U-50488 and (-)-Trans-(1S,2S)-U-50488.
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In Vivo——
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SynonymsU50488 | U-50488
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorOpioid Receptor
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number67197-96-0
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Formula Weight405.79
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Molecular FormulaC19H26Cl2N2O.HCl
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Purity>98% (HPLC)
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Solubility25 mM in H2O
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SMILESCN(C1CCCCC1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.CN(C1CCCCC1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl.Cl
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Chemical Nametrans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tao PL, et al. Eur J Pharmacol. 1994 May 2;256(3):281-6.
2. Suarez-Roca H, et al. J Pharmacol Exp Ther. 1993 Feb;264(2):648-53.
3. Su MT, et al. Br J Pharmacol. 1998 Feb;123(4):625-30.
4. Vonvoigtlander PF, et al. J Pharmacol Exp Ther. 1983 Jan;224(1):7-12.
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