JW55
CAS No. 664993-53-7
JW55( Tankyrase 1/2 Inhibitor IV )
Catalog No. M15535 CAS No. 664993-53-7
JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 33 | In Stock |
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| 25MG | 69 | In Stock |
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| 50MG | 111 | In Stock |
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| 100MG | 183 | In Stock |
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| 200MG | 272 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJW55
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NoteResearch use only, not for human use.
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Brief DescriptionJW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
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DescriptionJW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
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In Vitro——
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In Vivo——
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SynonymsTankyrase 1/2 Inhibitor IV
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorTNKS1| TNKS2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number664993-53-7
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Formula Weight434.48
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Molecular FormulaC25H26N2O5
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Purity>98% (HPLC)
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SolubilityDMSO, Ethanol: 100 mM
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SMILESO=C(C1=CC=CO1)NC2=CC=C(C(NCC3(C4=CC=C(OC)C=C4)CCOCC3)=O)C=C2
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Chemical NameN-(4-(((4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Waaler J, et al. Y Res. 2012 Jun 1;72(11):2822-32.
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