2-NP

CAS No. 65182-56-1

2-NP( —— )

Catalog No. M15475 CAS No. 65182-56-1

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 58 In Stock
5MG 52 In Stock
10MG 92 In Stock
25MG 187 In Stock
50MG 291 In Stock
100MG 458 In Stock
200MG 668 In Stock
500MG 1014 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    2-NP
  • Note
    Research use only, not for human use.
  • Brief Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.
  • Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65182-56-1
  • Formula Weight
    222.24
  • Molecular Formula
    C14H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: > 10 mM
  • SMILES
    C1=C/C(=C/2\C=CC3=C(N2)N=CC=C3)/C(=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lynch RA, et al. Y Res. 2007 Feb 1;67(3):1254-6
molnova catalog
related products
  • STA-21

    A small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM).

  • VV116

    VV116 is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus and SARS-CoV-2 infection.

  • MNK8?

    3-methyl-6- (naphthalen-1-yl)pyrimidine-2,4(1H, 3H)-dione is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells .