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2-NP

CAS No. 65182-56-1

2-NP( —— )

Catalog No. M15475 CAS No. 65182-56-1

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	58	In Stock
5MG	52	In Stock
10MG	92	In Stock
25MG	187	In Stock
50MG	291	In Stock
100MG	458	In Stock
200MG	668	In Stock
500MG	1014	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

2-NP
Note

Research use only, not for human use.
Brief Description

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.
Description

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

STAT1
Research Area

——
Indication

——

Chemical Information

CAS Number

65182-56-1
Formula Weight

222.24
Molecular Formula

C14H10N2O
Purity

>98% (HPLC)
Solubility

DMSO: > 10 mM
SMILES

C1=C/C(=C/2\C=CC3=C(N2)N=CC=C3)/C(=O)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lynch RA, et al. Y Res. 2007 Feb 1;67(3):1254-6

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