2-NP

CAS No. 65182-56-1

2-NP( —— )

Catalog No. M15475 CAS No. 65182-56-1

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 50 In Stock
10MG 87 In Stock
25MG 177 In Stock
50MG 282 In Stock
100MG 444 In Stock
200MG 646 In Stock
500MG 981 In Stock
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Biological Information

  • Product Name
    2-NP
  • Note
    Research use only, not for human use.
  • Brief Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.
  • Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65182-56-1
  • Formula Weight
    222.24
  • Molecular Formula
    C14H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: > 10 mM
  • SMILES
    C1=C/C(=C/2\C=CC3=C(N2)N=CC=C3)/C(=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lynch RA, et al. Y Res. 2007 Feb 1;67(3):1254-6
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