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Oxiconazole nitrate
CAS No. 64211-46-7
Oxiconazole nitrate( Ro 13-8996 )
Catalog No. M15441 CAS No. 64211-46-7
Oxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 5MG | 33 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 98 | In Stock |
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| 50MG | 169 | In Stock |
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| 100MG | 334 | In Stock |
|
| 200MG | 463 | In Stock |
|
| 500MG | 755 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameOxiconazole nitrate
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NoteResearch use only, not for human use.
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Brief DescriptionOxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm.
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DescriptionOxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm. (In Vitro):Oxiconazole (24 h; 0-40 μM) inhibits CRC cell growth.Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton.(In Vivo):Oxiconazole (50 mg/kg/day; IP; for 12 days) significantly restrains CRC cell growth.
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In VitroOxiconazole (24 h; 0-40 μM) inhibits CRC cell growth.Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton.Antifungal Activities of Oxiconazole.Cell Proliferation Assay Cell Line:HCT116, SW480, RKO, DLD-1, SW620, LoVo and NCM460 Concentration:0-40 μM Incubation Time:24 h Result:Exhibited inhibitory activity against HCT116, SW480, RKO, DLD-1, SW620, LoVo and NCM460 with IC50s of 25.86 μM, 27.34 μM, 21.01 μM, 25.56 μM, 21.75 μM, 24.87 μM and 126.4 μM.
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In VivoOxiconazole (50 mg/kg/day; IP; for 12 days) significantly restrains CRC cell growth. Animal Model:BALB/c nude mice (injected subcutaneously with HCT116 cells (1×107/mouse)Dosage:50 mg/kg/day Administration:IP; for 12 days Result:Significantly restrained CRC cell growth and showed no obvious side effects.
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SynonymsRo 13-8996
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PathwayMicrobiology/Virology
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TargetAntifection
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Recptor14-α Demethylase| LSS
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number64211-46-7
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Formula Weight492.14
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Molecular FormulaC18H13Cl4N3O·HNO3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESC1=CC(=C(C=C1Cl)Cl)CO/N=C(\CN2C=CN=C2)/C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Carrillo-Munoz AJ, et al. Rev Esp Quimioter. 2006 Jun;19(2):130-9.
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