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Oxiconazole nitrate
CAS No. 64211-46-7
Oxiconazole nitrate( Ro 13-8996 )
Catalog No. M15441 CAS No. 64211-46-7
Oxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 5MG | 33 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 98 | In Stock |
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| 50MG | 169 | In Stock |
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| 100MG | 334 | In Stock |
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| 200MG | 463 | In Stock |
|
| 500MG | 755 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameOxiconazole nitrate
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NoteResearch use only, not for human use.
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Brief DescriptionOxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm.
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DescriptionOxiconazole nitrate (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections such as athlete's foot, jock itch and ringworm. (In Vitro):Oxiconazole (24 h; 0-40 μM) inhibits CRC cell growth.Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton.(In Vivo):Oxiconazole (50 mg/kg/day; IP; for 12 days) significantly restrains CRC cell growth.
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In VitroOxiconazole (24 h; 0-40 μM) inhibits CRC cell growth.Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton.Antifungal Activities of Oxiconazole.Cell Proliferation Assay Cell Line:HCT116, SW480, RKO, DLD-1, SW620, LoVo and NCM460 Concentration:0-40 μM Incubation Time:24 h Result:Exhibited inhibitory activity against HCT116, SW480, RKO, DLD-1, SW620, LoVo and NCM460 with IC50s of 25.86 μM, 27.34 μM, 21.01 μM, 25.56 μM, 21.75 μM, 24.87 μM and 126.4 μM.
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In VivoOxiconazole (50 mg/kg/day; IP; for 12 days) significantly restrains CRC cell growth. Animal Model:BALB/c nude mice (injected subcutaneously with HCT116 cells (1×107/mouse)Dosage:50 mg/kg/day Administration:IP; for 12 days Result:Significantly restrained CRC cell growth and showed no obvious side effects.
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SynonymsRo 13-8996
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PathwayMicrobiology/Virology
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TargetAntifection
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Recptor14-α Demethylase| LSS
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number64211-46-7
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Formula Weight492.14
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Molecular FormulaC18H13Cl4N3O·HNO3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESC1=CC(=C(C=C1Cl)Cl)CO/N=C(\CN2C=CN=C2)/C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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(+)-Aromadendrene
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
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Altenuene
Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity against Staphylococcus aureus. Altenuene also exhibits cytotoxic activity against lung cancer cell line A549, breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC-1.
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Deoxylapachol
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induce fungal cell wall stress.
